Update

Within the next week, I'll have finished testing some of the new products.
In most likely order, the next posts will be:
L-Theanine
Yohimbine HCL
Hordenine
Higenamine
IDRA-21
Preworkout combination explanation, including several new supplements.

Picamilon

Picamilon is a supplement that first gained significant popularity around the middle of last year.  Around October, I bought 25 grams for about $14 because of its ever-touted anti-anxiety effects.  While I did eventually get the desired effect, what ensued immediately after dosage was intense and unexpected.

The first time I used it, I took 150mg dissolved in water.  Within a few hours, all of my confidence was gone and I was constantly on the verge of tears.  I slept it off and tried again the next night. This time the crippling was about 25% as intense. After that, I felt the anxiety-relieving effects, but I really had no need for them.

The bad side effects seem limited to only my experience. In theory, It should trigger a GABA-like response, relieving anxiety  Picamilon is a bonded form of GABA and Niacin, which is separated into its main components upon crossing the blood-brain barrier.  The blood-brain barrier is all important in any drug's efficacy, if it is supposed to act on the brain.

It has widespread use in Russia, where it is prescribed as a treatment for stroke recovery, senile psychosis, alcohol cessation, acute alcohol poisoning, migraines, depression, some cerebral blood flow issues, and certain types of glaucoma.

As far as I can tell, my experience is fairly unique.  Out of the 30+ times I have taken it, the depression and extreme lethargy has happened 6 or 7 times.  The way it works in most people is as a fast acting mild anxiolytic.  It has less addiction/tolerance problems than phenibut, and if all you want is a dulled reality instead of light intoxication, Picamilon will probably work well for you.

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Schizandrol A

This is the first post about something that isn't typically used for studying or learning, though some do and claim that it has a calming effect that also enhances focus.  In my time with schizandrol A, I experienced nothing of the sort.

Schizandrol A is commonly used to enhance/increase the effects of other stimulants because of its adaptogenic qualities.  While I have not done this myself, some say that when taken with relaxing agents, schizandrol potentiates those too.  This effect is most often mentioned when the commenter is using whole plant extract, not just isolated compound A.

Last year my stimulant stack for my preworkout included a dose of it, along with yohimbine hcl when fasted, PEA, caffeine, and other  compounds.  The common effect I noticed when schizandrol was used with the other ingredients was that for several hours, my pupils constantly dilated and contracted.  I wasnt aware of it until I noticed it in a mirror after someone told me.  By process of elimination, I figured out that Schizandrol was the cause. This effect had a direct relationship with how much or little I used. At higher dosages, my iris was turned into a thin blue striped band around a quivering black spot when dilated.

When asked for my opinion on what ingredients are best for a preworkout blend if someone wants the pump and a stimulating rush; I responded with the following list

AAKG
Citrulline
Beta alanine
Creatine, optional
Caffeine
DMAA
Schizandra

After recommending this on /fit/ 2 years ago, someone accused me of stealing Jack3d's formula.

After looking up what it actually was, it turned out they were right.  Though part of its legend has come from its lack of availabity, being the "One pwo to rule them all" according to many, Jack3d original was very well done.

Before I could mix and match it with some of my newer purchases, I lost the sachet of powder.  This is a definite reorder for me.  I'll be trying it alongside DMAA for the first time soon.


Now would be a good time to mention that nothing I say should be taken as law, all your decisions should be researched beyond the general overview I provide, and none of this constitutes medical advice.  Happy lifting.

Oxiracetam

This is one of my favorites in the racetam family.

It has very prosocial effects, and noticeably increases my working memory.  For lecture classes, it feels like I'm back in highschool when I could get away without notes.  That said, I take even better notes when I use Oxi.

Oxi is semi famous for its stimulant effect.  Lower doses give the same creative mindset that Piracetam does, but higher doses can be too much for some people who are sensitive to stimulants. You're still creative and functioning at a high level, but the impulsiveness can get out of hand when paired with other stimulants. This morning before writing this, I left accounting class with 3 diagrams for inventions and most of a database written for a project, along with acing both quizzes in class.  You get an incredible ability to change your train of thought at any given time, and your thinking process is elevated as with any racetam.

Looking into the studies done on oxiracetam, data shows that it is most effective on hippocampally mediated functions, such as consolidation information to short and long term memory, and spatial reasoning/navigation.

Final Verdict

Social Effects:  Better social ability in general
Learning effect: Better creation of memory, items learned are retained almost perfectly
Cost Factor:  Relatively high cost, best used when needed.  About 30cents per dose, which adds up quickly.
Effective Time: Oxiracetam sets in fairly quickly, and you will usually feel it. My threshold is about half a gram, and it takes about this much to have an actual effect too. A dose of 2 grams is fairly intense and impressive as far as you ability to process and memorize even abstract information
Best Features: Heightened focus, more fun socially, easy memory.
X- Factor: It tastes sweet! Also synergizes well with Noopept+Rhodiola

Phenylpiracetam

Lifechanging.
Simply lifechanging.  For those familiar with anabolic steroids, this is the halotestin of the racetam family It is powerful and reliable.  If you take it when you need it, and you get what you want.  If you want something motivating, non addictive, and energizing, then there isn't a replacement for phenylpiracetam.

My first dose was about 200mg, and in a short amount of time, I could feel that my thinking was different.  Every decision had a confident snap to it.  My personality turned into high energy and hyperactive type, which is a huge variation for me.  On the way back up to my apartment, I caught myself dancing in the elevator.  One of my very few rules in life is that I do not dance, not even to save my life.  No movements that I can make should even be called dancing, that's an insult to more talented dancers than I, such as 2013 Miley Cyrus.

This helps with crunch-time studying, and is best taken with rhodiola and noopept in my experience.  These combine for a high-energy focus that helps you retain nearly everything.

Supplementing with this greatly intensifies motivation, and because of that I advise that it be used sparingly, and at critical times.  It has an energizing effect, and is banned by the World Anti-Doping Agency.

Final Verdict

Social Effects: Irritability.
Learning effect: Motivational, but a bit erratic.  Learn to focus and this is quite a tool
Cost Factor: Can cost as much as $1 per dose (200mg)
Effective Time: Very noticeable energizing effect.  Onset varies with meal timing, but is quick
Best Features: Increased endurance, resistance to cold, very energizing.

Mine was purchased from Liftmode.  Their link is in the "Trusted" box in the sidebar, for good reason.  Good prices and real products.  They also let you pay through your amazon account.

Rhodiola Rosea

This was first brought to my attention by an Anon on /fit/ as part of a list of supplements he took for recovery.  I looked into it a bit, and it seemed interesting, with good bang for your buck.
I found that seven double blind clinical studies, Rhodiola Rosea dosing was found to definitely decrease fatigue with a notable potency. 4 studies show that it raises cognition and subjective level of well being. It can lower depression and the rate of perceived exertion. Also lowers lactate production, stress, and muscle damage.


Usually the anecdote I give along with this is how I felt so good after my heavy day on bench that I did a speed set and managed 225x12 at the end.  Its a feelgood supplement and is incredibly cheap, especially considering the effect.  Besides muscle endurance under strain, there is also a notable increase to attention and focus endurance under strain.  As long as my motivation stays high, I can continue focusing on one topic for extended periods of time, regardless of lack of sleep or interest level.

I'm planning to test its effectiveness soon (a study measuring the increase in number of pushups to failure from trial to trial). Even though the sample size will be small, something quantifiable is useful.  If you have it yourself and want to contribute, please do so: there is a contact form at the bottom of the page for this sort of thing.

Final Verdict

Social Effects:  Not much is noticeable here, besides longer attention span and greater interest in other people.
Learning effect: Most of its benefit towards learning is produced buy its anti-fatigue effects and ability to extend attention span.
Cost Factor: Can be gotten as cheap as $3 per ounce, though there is no guarantee of potency.  what you buy in precapsulated for will be standardized for rosavins and other helpful chemicals.  The raw powder works well as a small part of an herb rub for grilled chicken.
Effective Time: Not specifically known or that noticeable. It tends to come on steadily rather than "hit," but the effects are actively noticeable. Sort of an energizing effect.
Best Features: works like a +5% buff to most of your body and psyche

Ephedrine

Ephedra, a plant containing ephedrine and pseudoephedrine, has been in Chinese medicine for over 5000 years.  The substance we use for mental effects is Ephedrine, a stimulant of the andrenergic system.  Its use increases noradrenaline's activity at the receptors.  In other words, skipping over the science, ephedrine gives you more energy, counteracts muscle wasting and keeps you more awake.  In America, its available to adults over the counter at up to 9 grams of ephedrine per 30 day period.  In terms of 60 tablet boxes of bronkaid, this is the equivalent of 6 boxes per month, so you really shouldn't have any worries about limited availability.  The FDA declared all weightloss products containing ephedrine alkaloids "adulterated" and therefore banned, while antiasthmatic and other respiratory products with ephedrine are still allowed for sale, just with the restrictions given above

A few warnings I have to give with ephedrine: don't consider using it if you have any sort of heart condition, oversensitivity to stimulants, if you are pregnant, or if you are on antidepressants.

Ephedrine is often used as part of an EC or ECY stack, the C and Y being caffeine and yohimbine hcl.  The dosage, frequency, and run time advice can be found on other sites with airtight liability disclaimers, unlike this one. Ill be covering this, and whatever findings I have from combining it with chromium picolinate, an insulin mimetic, and octopamine, a fat loss agent, in a later post.

As for my experience with ephedrine, It may be my favorite stimulant.
On its own it increases aggression and decreases reaction time, but when paired with piracetam, the aggression seems mitigated to being socially useful rather than intrusive or disruptive.  and EP stack is probably the most basic and cheapest enhancement someone can make to their life, especially if they feel that they are the type who over-thinks social situations to the point where they are disadvantaged.  By all account, adding intelligence to the impulsiveness brought on by ephedrine will make you feel and appear more "Alpha"
This is the reason its one of the template stacks that I recommend on /fit/ the most often.  The dosage that most people use is about 50-75mg a day, spread out.